Primobolan depot bayer has antiviral, immunomodulatory, antiproliferative and antitumor activity.
Interferon alpha interact with cognate receptors on cell surfaces triggers a complex chain changes within the cell. It is assumed that these processes are associated with the prevention of viral replication in the cell, the inhibition of cell proliferation and immunomodulatory effects of interferon. Interferon alpha has the ability to stimulate the phagocytic activity of macrophages and cytotoxic activity of T-cells and “natural killer”. These properties of interferon alpha and is caused by a therapeutic effect .
– acute hepatitis B
– chronic active hepatitis B,
– chronic hepatitis C
– tick-borne encephalitis;
– hairy cell leukemia,
– chronic myeloid leukemia,
– renal cell carcinoma
– Kaposi’s sarcoma on the background of AIDS
– cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome),
– malignant melanoma.
The use in pregnant women and nursing mothers
Primobolan depot bayer expected therapeutic effect for the mother should be given to pregnant women and nursing mothers only if the explicit superiority in comparison with the possible adverse effects on the fetus (especially in the first 3 months), or a child.
Dosing and dose
Is used for intramuscular or subcutaneous injection, immediately prior to use by dissolving the contents of a vial or ampoule of 1 ml of water for injection. The drug dissolved rapidly, regardless of the dose contained in a vial or ampoule. The solution of the drug is a colorless, clear or slightly opalescent liquid. Does not contain preservatives, so that only a freshly prepared solution should be used to prevent bacterial contamination.
Acute hepatitis B (light, medium, heavy and severe) is administered at 1 million twice a day for 5-6 days and then the dose was reduced to 1 million per day and is administered for a further 5 days. If necessary (after controlling biochemical blood tests to assess the functional state of the liver), the treatment can continue for 2 weeks, during which the drug is administered at 1 million twice a week.
Is most effective at the beginning of jaundice period until the 5th day of jaundice, at a later date the appointment of the drug less effective. Primobolan depot bayer is not effective in developing hepatic coma and cholestatic disease course.
In chronic active hepatitis B drug prescribed by 3-6 million ME three times a week for 24 weeks. If after administration for 12 weeks, there is no clinical, biochemical improvement and / or disappearance of HBsAg, treatment Realdiron overturned.
In chronic hepatitis C drug is administered at 3 million ME three times a week for 24 weeks. If after administration for 4 weeks is not observed decrease in plasma activity, the dose was increased to 6 million ME three times a week. Realdiron Treatment stopped if after 12 weeks of use, and the drug is not observed clinical, biochemical improvement. achat steroides winstrol effet achat steroide